Porcine rotavirus-like virus (group B rotavirus): characterization and pathogenicity for gnotobiotic pigs
نویسندگان
چکیده
منابع مشابه
In vitro detection of porcine rotavirus-like virus (group B rotavirus) and its antibody.
Four isolates of porcine rotavirus-like virus (PRVLV) infected MA104 cells and induced syncytium formation after low-speed centrifugation of the inoculum onto the monolayer. Ten of 44 (23%) Ohio swine sera had PRVLV antibodies when tested by indirect immunofluorescence, using PRVLV-infected MA104 cell monolayers as antigen.
متن کاملPorcine pararotavirus: detection, differentiation from rotavirus, and pathogenesis in gnotobiotic pigs.
Some characteristics of a newly recognized porcine enteric virus are described. Tentatively, the virus was referred to as porcine pararotavirus (PaRV) because it resembled rotaviruses in respect to size, morphology, and tropism for villous enterocytes of the small intestine. However, it was antigenically distinct from porcine, human, and bovine rotaviruses and reoviruses 1, 2, and 3, and the el...
متن کاملModeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs
BACKGROUND Rotavirus vaccines have poor efficacy in infants from low- and middle-income countries. Gut microbiota is thought to influence the immune response to oral vaccines. Thus, we developed a gnotobiotic (Gn) pig model of enteric dysbiosis to study the effects of human gut microbiota (HGM) on immune responses to rotavirus vaccination, and the effects of rotavirus challenge on the HGM by co...
متن کاملViremia and nasal and rectal shedding of rotavirus in gnotobiotic pigs inoculated with Wa human rotavirus.
Respiratory symptoms with rotavirus shedding in nasopharyngeal secretions have been reported in children with and without gastrointestinal symptoms (Zheng et al., 1991, J. Med. Virol. 34:29-37). To investigate if attenuated and virulent human rotavirus (HRV) strains cause upper respiratory tract infections or viremia in gnotobiotic pigs, we inoculated them with attenuated or virulent HRV intran...
متن کاملPathogenicity of 2 Porcine Deltacoronavirus Strains in Gnotobiotic Pigs
To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21-120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1985
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.21.3.340-345.1985